Clinic for Orthopaedics and Trauma Surgery Bonn

Third-party funded projects

BONFOR-Forschungskommission, Medizinische Fakultät der Universität Bonn:

Period of sponsorship: 1 January 2010 – 1 January 2011 (renewable for 1 further year following a positive intermediate evaluation)
Subsidies: 55,000 €
Cooperation partner: Klinische Forschergruppe 208 (DFG) Labor für Oralbiologische Forschung der Poliklinik für Kieferorthopädie; Zentrum für Zahn-, Mund- und Kieferheilkunde; Rheinische-Friedrich-Wilhelms-Universität Bonn
Project: Experimental in-vitro study fort he evaluation of modern biomaterials when Bone-Tissue-Engineering for the treatment of large bone defects in orthopaedic surgery as well as dental and oral medicine.

Project manager: Dr. med. S. Gravius

Fa. Peter Brehm (Weisendorf, D),
Tutogen Medical GmbH (Neunkirchen am Brand, D), Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 July 2009 – 31 December 2010
Subsidies: 132,500 €
Project: Experimental in-vivo study to evaluate the application possibilities of innovative bone substitutes in comparison with allogeneic and autologous spongiosa in loaded defect areas in case of acetabular periprosthetic bone defects using the animal model sheep.

Project manager: Dr. med. S. Gravius

Fa. Peter Brehm (Weisendorf, D),
Tutogen Medical GmbH (Neunkirchen am Brand, D), Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 July 2009 – 31 December 2010
Subsidies: 132,500 €
Project: Experimental in-vivo study to evaluate the application possibilities of innovative bone substitutes in comparison with allogeneic and autologous spongiosa in loaded defect areas in case of acetabular periprosthetic bone defects using the animal model sheep.

Project manager: Dr. med. S. Gravius

Fa. Peter Brehm (Weisendorf, D),
Tutogen Medical GmbH (Neunkirchen am Brand, D), Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 July 2009 – 31 December 2010
Subsidies: 132,500 €
Project: Experimental in-vivo study to evaluate the application possibilities of innovative bone substitutes in comparison with allogeneic and autologous spongiosa in loaded defect areas in case of acetabular periprosthetic bone defects using the animal model sheep.

Project manager: Dr. med. S. Gravius

AFOR Stiftung:

Period of sponsorship: 1 January 2010 – 1 January 2017

Subsidies: 10,000 €
Project: Significance of the gene expression analysis of periprosthetic tissue samples in septic and aseptic loosened hip endoprostheses – a clinical and diagnostic interdisciplinary research project with a future

Project manager: Dr. med. S. Gravius

Fa. Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 January 2010 – 1 January 2013
Subsidies: 1,500 €
Project: Health economic evaluation of educational costs

Project manager: Dr. med. P. Göbel

Fa. Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 January 2010 – 1 January 2013
Subsidies: 1,500 €
Project: Health economic evaluation of educational costs

Project manager: Dr. med. P. Göbel

Deutsche Arthrose-Hilfe:

Period of sponsorship: 1 January 2010 – 1 January 2012

Subsidies: 159,789 €

Cooperation partner: Labor für Oralbiologische Forschung der Poliklinik für Kieferorthopädie; Zentrum für Zahn-, Mund- und Kieferheilkunde; Rheinische-Friedrich-Wilhelms-Universität Bonn Institut für Klinische Chemie und Pharmakologie, Rheinische-Friedrich-Wilhelms- Universität Bonn Institut für Medizinische Biometrie, Universität Bonn

Project: Significance of the RANK/RANKL/OPG-system and new markers of infection PCT and LBP and their interaction with anti-inflammatory cytokines (IL-10) and growth-factors (IL-1β, TNF-α, IL-6; IL-8), anti-inflammatory cytokines (IL-10) and growth-factors (M-CSF) in differential diagnostics of septic vs. aseptic loosened prostheses.

Project manager: Dr. med. S. Gravius

Simpirica Spine USA:

Period of sponsorship: 1 January 2010 –31 December 2011
Subsidies: 12,000 €
Project: LimiFlex-Study
Project manager: PD Dr. med. R. Pflugmacher

Simpirica Spine USA:

Period of sponsorship: 1 January 2010 –31 December 2011
Subsidies: 12,000 €
Project: LimiFlex-Study
Project manager: PD Dr. med. R. Pflugmacher

AFOR Stiftung:

Period of sponsorship: 1 January 2010 – 1 January 2017

Subsidies: 10,000 €
Project: Significance of the gene expression analysis of periprosthetic tissue samples in septic and aseptic loosened hip endoprostheses – a clinical and diagnostic interdisciplinary research project with a future

Project manager: Dr. med. S. Gravius

BONFOR-Forschungskommission, Medizinische Fakultät der Universität Bonn:

Period of sponsorship: 1 January 2010 – 1 January 2011 (renewable for 1 further year following a positive intermediate evaluation)
Subsidies: 55,000 €
Cooperation partner: Klinische Forschergruppe 208 (DFG) Labor für Oralbiologische Forschung der Poliklinik für Kieferorthopädie; Zentrum für Zahn-, Mund- und Kieferheilkunde; Rheinische-Friedrich-Wilhelms-Universität Bonn
Project: Experimental in-vitro study fort he evaluation of modern biomaterials when Bone-Tissue-Engineering for the treatment of large bone defects in orthopaedic surgery as well as dental and oral medicine.

Project manager: Dr. med. S. Gravius

Fa. Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 November 2009 – 31 October 2011
Subsidies: 5,000 €
Project: Prospective studies of radiological and clinical results regarding percutaneous treatment of vertrebral body fractures using the fixation system S4 FRI (Fracture Reduction Instruments)
Project manager: Prof. Dr. med. C. Burger

Fresenius Kabi Deutschland GmbH:

Period of sponsorship: 01.10.2009 - 01.06.2010
Subsidies: 1,466 €
Cooperation partner: Institut für Ernährungs- und Lebenswissenschaften, Universität Bonn
Project: Prevention of hypovitaminosis regarding trauma surgical patients with impaired healing
Project manager: Dr. med. H. Goost, Dipl. Oec. S. Blaß

Fa. Bayer Vital GmbH, Tuttlingen:

Period of sponsorship: 1 July 2009 – 1 January 2015
Subsidies: 6,800 €
Project: Analysis of food, energy and nutrient supply as well as the nutritional status of surgically working physicians at the Surgical Centre of the University Hospital Bonn

Project manager: Dr. med. H. Goost

Fa. Bayer Vital GmbH, Tuttlingen:

Period of sponsorship: 1 July 2009 – 1 January 2015
Subsidies: 6,800 €
Project: Analysis of food, energy and nutrient supply as well as the nutritional status of surgically working physicians at the Surgical Centre of the University Hospital Bonn

Project manager: Dr. med. H. Goost

Fa. Peter Brehm (Weisendorf, D),
Tutogen Medical GmbH (Neunkirchen am Brand, D), Aesculap AG (Tuttlingen, D):

Period of sponsorship: 1 July 2009 – 31 December 2010
Subsidies: 132,500 €
Project: Experimental in-vivo study to evaluate the application possibilities of innovative bone substitutes in comparison with allogeneic and autologous spongiosa in loaded defect areas in case of acetabular periprosthetic bone defects using the animal model sheep.

Project manager: Dr. med. S. Gravius

BMBF (13N10472):

Period of sponsorship: 1 June 2009 – 31 May 2012
Subsidies: 1,970,154.00 €
Joint project: VoTeKK Preparation for terrorist attacks, crises and catastrophes. Web-based interdisciplinary information and training platform for protective services and rescue teams, medical staff as well as the population to prepare for major emergencies.
Project executing organisation: BMBF (Federal Ministry of Education and Research)
Cooperation: Consortium from a total of 12 cooperation partners: Deutsches Institut für Katastrophenmedizin (Tübingen), Bundesamt für Bevölkerungsschutz und Katastrophenhilfe Robert Koch Institut, „Die Medialen" , T-Systems MMS, DGU, BAND AGNNW, ESTES, DGKM, DIVI
Project managers: P. Fischer, Dr. Kabir

BONFOR-Forschungskommission, Medizinische Fakultät der Universität Bonn:

Period of sponsorship: 1 January 2010 – 1 January 2011 (renewable for 1 further year following a positive intermediate evaluation)
Subsidies: 55,000 €
Cooperation partner: Klinische Forschergruppe 208 (DFG) Labor für Oralbiologische Forschung der Poliklinik für Kieferorthopädie; Zentrum für Zahn-, Mund- und Kieferheilkunde; Rheinische-Friedrich-Wilhelms-Universität Bonn
Project: Experimental in-vitro study fort he evaluation of modern biomaterials when Bone-Tissue-Engineering for the treatment of large bone defects in orthopaedic surgery as well as dental and oral medicine.

Project manager: Dr. med. S. Gravius

Peter Brehm Chirurgie-Mechanik e.K.:

Period of sponsorship: 1 January 2009 – 1 November 2011
Subsidies: 4,985 €
Project: Clinical follow-up examination of MRP-titanium-hip-revision-stem prothesis

Project manager: Prof. Dr. med. D. C. Wirtz

Fa. Aesculap, Tuttlingen:

Period of sponsorship: October 2008 – October 2009
Subsidies: 72,269 €
Project: "Wear debris reaction in the spinal region of rabbits"
Project manager: Dr. K. Kabir

BMBF ( 01 EQ 0802):

Period of sponsorship: 1 July 2008 – 30 June 2010
Subsidies: 233,738 €
Cooperation partner: OrthoMIT-consortium
Project: Joint research project ”Minimally invasive orthopaedic therapy: medical specification and evaluation”

Project managers: Prof. Dr. D. C. Wirtz, Dr. M. Müller, Dr. K. Kabir

Aesculap, Tuttlingen, Invibio Ltd.:

Period of sponsorship: 1 January 2008 – 30 November 2010 Fa Aesculap, Tuttlingen
Period of sponsorship: 1 January 2010 – 31 August 2011 Invibio Ltd.
Subsidies: 155,211 €
Project: Wear debris reaction in the spinal region of rabbits
Project manager: Dr. K. Kabir

Aesculap, Tuttlingen, Invibio Ltd.:

Period of sponsorship: 1 January 2008 – 30 November 2010 Fa Aesculap, Tuttlingen
Period of sponsorship: 1 January 2010 – 31 August 2011 Invibio Ltd.
Subsidies: 155,211 €
Project: Wear debris reaction in the spinal region of rabbits
Project manager: Dr. K. Kabir

BMBF (01 EQ 0402):

Period of sponsorship: 01 December 2007 – 1 December 2008
Subsidies: 80,000 €
Percentage Clinic for Orthopaedics and Trauma Surgery Bonn: 27,500 €
Joint project: Skills Lab
Cooperation partner: Klinik für Anästhesiologie, Klinik für Kinderheilkunde
Project manager: P. Fischer

Fresenius Kabi Deutschland GmbH:

Period of sponsorship: 01 October 2007 – 01 March 2009
Subsidies: 30,000 €
Cooperation partner: Institut für Ernährungs- und Lebenswissenschaften, Universität Bonn
Project: Prevention of hypovitaminosis regarding trauma surgical patients with impaired healing

Project managers: Dr. H. Goost, Dipl.Oec. S. Blaß

Medizinische Fakultät Bonn:

Period of sponsorship: 1 April 2005 – 1 April 2008 (renewable until 2010 following a positive intermediate evaluation)
Subsidies: 13 Mio. €
Percentage Clinic for Orthopaedics and Trauma Surgery Bonn: 70,000 €
Joint project: OrthoMIT (orthopaedic therapy with innovative technology) within the BMBF-Program SOMIT (Gentle Surgery with innovative technology)
Project executing organisation: BMBF (Federal Ministry of Education and Research) at the DLR (Deutsches Zentrum für Luft- und Raumfahrt e.V.)
Cooperation: Consortium from a total of 28 partners (Universitätskliniken/ -institute Aachen, Dresden, Erlangen, Bochum, Bonn; Kompetenzzentren Medizintechnik AKM (Aachen), TELTRA (Bochum), KMR (Bochum); Industriefirmen [among others Siemens AG / Erlangen, Aesculap AG / Tuttlingen])
Project manager: Prof. Dr. D. C. Wirtz